General information
Organisation
The French Alternative Energies and Atomic Energy Commission (CEA) is a key player in research, development and innovation in four main areas :
• defence and security,
• nuclear energy (fission and fusion),
• technological research for industry,
• fundamental research in the physical sciences and life sciences.
Drawing on its widely acknowledged expertise, and thanks to its 16000 technicians, engineers, researchers and staff, the CEA actively participates in collaborative projects with a large number of academic and industrial partners.
The CEA is established in ten centers spread throughout France
Reference
2025-35123
Description de l'unité
l'Institut de Biologie François-Jacob a pour mission de conduire des recherches en radiobiologie et radiotoxicologie, en génomique humaine, en génomique environnementale et en recherche translationnelle dans le domaine des affections neurodégénératives, infectieuses et hématologiques, en s'appuyant sur les plateformes de haute technologie et l'expertise des unités de la DRF situées sur les sites de Fontenay aux Roses et d'Evry.
IDMIT research centre, at Fontenay-Aux-Roses (30mins south of Paris by public transport) in France provides an environment that fosters education and training opportunities that are ideal to nurture an early career in research. Research at IDMIT brings together. 150 scientists working on common fundamental pre-clinical to clinical immunological challenges, related to innate and adaptive immunity, in the context of viral infections and regulation of immune disorders. IMDIT boasts outstanding technological facilities, including: BSL3 laboratories, cytometry, molecular biology, and in vivo imaging platforms.
Position description
Category
Health
Contract
Postdoc
Job title
Postdoctoral position in neuro-viral immunology H/F
Subject
Study immune mechanisms implicated in restriction of viral reactivation.
Contract duration (months)
24
Job description
The position is available in the HSV group led by Professor Marc Labetoulle, for characterisation of newly identified immune responses involved in restricting reactivation of latent HSV1 reservoirs, to be exploited for protective and therapeutic interventions. HSV1 will infect almost all humans at some time in their life, to establish a persistent latent state in sensitive neurons of the trigeminal ganglia. Stress induces reactivation of lytic replication, with diseases caused at peripheral sites by lytic inflammatory viral replication episodes. These include painful cold sores, potentially blinding ocular herpetic keratitis, and HSV1 is implicated in Alzheimer’s disease. The candidate will use advanced molecular and immunology approaches, to further define functional aspects of these immune signatures that are essential for eliciting immunity to reactivation.
Applicant Profile
Qualification requirements and skills
We seek a hardworking, highly motivated and enthusiastic candidate with:
- A recently acquired PhD in immunology, virology, or a similar field
- A strong background in cellular and molecular biology
- Strong understanding of immunology
- Proficiency in professional English
- Competent computer skills
- High level report writing and oral presentational skills
Experience required
- Immunology methodologies
- tissue culture
- flow cytometry
- experimentation in vivo
- working in ≥ BSL 2 containment
Interested applicants should submit a complete CV, a brief description of their research achievements interests and motivations, and name and contact details for three referees to Professor Marc Labetoulle: mlabetoulle@15-20.fr
Applications close 16 March 2025
Position location
Site
Fontenay-aux-Roses
Job location
France
Location
Fontenay-aux-Roses
Requester
Position start date
01/09/2025
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