General information
Organisation
The French Alternative Energies and Atomic Energy Commission (CEA) is a key player in research, development and innovation in four main areas :
• defence and security,
• nuclear energy (fission and fusion),
• technological research for industry,
• fundamental research in the physical sciences and life sciences.
Drawing on its widely acknowledged expertise, and thanks to its 16000 technicians, engineers, researchers and staff, the CEA actively participates in collaborative projects with a large number of academic and industrial partners.
The CEA is established in ten centers spread throughout France
Reference
2025-34994
Description de l'unité
The Laboratory « Innovative technologies for Detection and Diagnostics » (Li2D), part of the JOLIOT Institute, conducts pioneering research in diagnostics and detection, underpinned by recognized expertise in microbiology, immunology, genomics, proteomics, and bioinformatics, alongside high-resolution mass spectrometry. The ProGénoMix platform @Li2D is a state-of-the-art proteomics facility specializing in proteomics, proteogenomics, metaproteomics, and multi-omics. The platform is dedicated to advancing our understanding of complex biological systems, applying this knowledge to medical and environmental diagnostics, and offering cutting-edge proteomics methodologies to support the broader scientific community. A key focus of the platform is the development of mass spectrometry methodologies for the identification and characterization of pathogens (tandem mass spectrometry-based proteotyping, shotgun proteomics, targeted proteomics), as well as for the study of more complex samples, such as microbiota (metaproteomics). The platform is one of the six nodes of the INBS ProFI, network of excellence in proteomics in France. The platform currently runs six tandem mass spectrometers including Astral and Exploris systems.
Position description
Category
Life Sciences
Contract
Fixed-term contract
Job title
MASS SPECTROMETRY ENGINEER
Socio-professional category
Executive
Contract duration (months)
24
Job description
The candidate will operate tandem mass spectrometers and carry out proteomics experiments, from sample preparation to data analysis. He/she will interact and collaborate with other team members and with scientists involved in the projects. Responsibilities will include preparing and delivering technical presentations for internal and external meetings.
The selected candidate will receive comprehensive training in the use and maintenance of all equipment within the platform, and the use of both in-house and external data analysis tools.
The main tasks are:
Operation and maintenance of various chromatography apparatus and mass spectrometers
Sample preparation prior to MS analysis
Acquisition and analysis of proteomic data, using dedicated software
Development of methods for sample preparation, chromatographic separation and optimization of data acquisition.
To apply, please send an email to lucia.grenga@cea.fr & jean.armengaud@cea.fr before January 18th, with your curriculum vitae, letter of motivation, copy of academic transcripts and reference letters.
Applicant Profile
REQUIRED Knowkedge and qualifications
M2 or engineer, with experience, or PhD
Excellent training in Analytical Chemistry and Protein Biochemistry
Strong experience in chromatography and mass spectrometry, ideally “genious handyman”
Appreciated experience of experimental approaches in proteomics, such as label-free shotgun proteomics, TMT-labelling, PTMs or crosslinks
· Appreciated experience with DIA methods and corresponding softwares
LANGUAGE SKILLS
Proficient in French and English
Soft skills
Ambition and commitment to learning
Ability to work in a team and on multiple projects in parallel
Organization and critical thinking
Position location
Site
Marcoule
Job location
France, Occitanie, Gard (30)
Location
Marcoule
Requester
Position start date
01/03/2025
Create candidate area
