General information
Organisation
The French Alternative Energies and Atomic Energy Commission (CEA) is a key player in research, development and innovation in four main areas :
• defence and security,
• nuclear energy (fission and fusion),
• technological research for industry,
• fundamental research in the physical sciences and life sciences.
Drawing on its widely acknowledged expertise, and thanks to its 16000 technicians, engineers, researchers and staff, the CEA actively participates in collaborative projects with a large number of academic and industrial partners.
The CEA is established in ten centers spread throughout France
Reference
2025-35567
Division description
Leti, a technology research institute at CEA Tech, is a global leader in miniaturization technologies enabling smart, energy-efficient and secure solutions for industry.
Leti tackles critical challenges in healthcare, energy and digital migration. From sensors to data processing and computing solutions, Leti's multidisciplinary teams deliver solid expertise, leveraging world-class pre-industrialization facilities.
Description de l'unité
Within the Department of Technologies for Health Innovation, the multidisciplinary team of the Microfluidic Systems and Bioengineering Laboratory designs and builds microfluidic systems for applications in biology and healthcare.
Position description
Category
Biology, biophysics and biochemistry
Contract
Fixed-term contract
Job title
Microfluidics Research Engineer
Socio-professional category
Executive
Contract duration (months)
24
Job description
Chronic and serious cases of diabetes type 1 are currently treated by islet grafts. These transplants have a miraculous effect on the quality of life of patients. However, the efficacy and survival rate of the implant diminishes over the years.
At CEA-Leti we are starting a long-term ambitious project in collaboration with the Grenoble Alpes University Hospital to develop biological twin models following patients’ transplants. We aim to provide clinicians with insights into the patient’s immune response allowing them to better make clinical decisions.
We are currently seeking a motivated and talented researcher to join our team.
Our objectives are to design, prototype and validate a microfluidic platform with monitoring and multisensing approaches enabling the study of interactions between transplanted islets and immune cells isolated from the islet recipient, as a predictive tool for clinicians of islet transplant rejection and immune relapse and/or loss of efficacy of immunosuppressive treatment.
You will contribute to the development of a modular microfluidic platform dedicated to organ-on-chip applications. The position has a strong accent on microfluidic experimentation in order to ensure robustness and reliability of the system. In close collaboration with experts in biology, manufacturing and sensor technologies, you will be responsible for the microfluidic aspects of the biological experiments. The position requires you to be pragmatic and hands-on in your role as a facilitator.
Your activities will include:
- microfluidic experimentation with or without biological components
- characterization of microfluidic devices
- setting up test environments
- using and improving software for control and acquisition
- analysis and interpretation of results
Applicant Profile
Engineer (MSc) and/or doctor (PhD), you have strong expertise in microfluidic development.
Knowledge in microfluidic development is required and experience in organ-on-chip would be a plus.
Attracted by a multi-disciplinary environment and technological innovation, you are committed to achieving results in your projects.
Motivated by experimental work (bench work), you know how to work as part of a team with a wide variety of people.
Rigor, dynamism and organizational skills will be particularly appreciated. Fluency in English is a must.
In line with CEA's commitment to the integration of disabled people, this position is open to all. The CEA offers accommodation and/or organizational possibilities for the inclusion of disabled workers.
Position location
Site
Grenoble
Job location
France, Auvergne-Rhône-Alpes, Isère (38)
Location
Grenoble
Candidate criteria
Languages
English (Intermediate)
Requester
Position start date
01/05/2025